A Mini-Review on Chitosan Microsphere Drug Delivery

The study aims to determine the drug therapy of any disease attain desired therapeutic concentration in plasma or at site action and maintain it for entire duration treatment. A on being used conventional dosage forms leads unavoidable fluctuations leading under medication overmedication increased frequency dose administration as well poor patient compliance. To minimize degradation loss, prevent harmful side effects increase bioavailability various delivery targeting systems are currently development. Handling treatment severe conditions has necessitated development innovative ideas modify techniques. Drug carrier include polymers, micelles, microcapsules, Liposomes lipoproteins etc. Different polymer carriers exert different delivery. Synthetic polymers usually no biocompatible, non-biodegradable expensive. Natural such chitin chitosan devoid problems. Chitosan is a biodegradable, nontoxic natural with excellent film-forming ability. Being cationic character, able react polyamines giving rise polyelectrolyte complexes. Hence become promising preparation microspheres nanospheres microcapsules. This review focuses preparation, characterization their role novel systems. also process variables factors that affect release drugs from microspheres.